Tonight, we have "a closer look" at cutting-edge medicine that's offering new hope for some patients with very severe depression. More than 21 million Americans suffer from depression. For about 4 million, nothing helps. Not drugs. Not psychotherapy. Nothing. Now, a highly experimental new treatment is being tried on only 17 patients so far.
But it's provided real relief to eight of them, as we say new and highly experimental. Here's John Mckenzie. The pictures are crystal clear, just like the memories - for Diane Hire, painful reminders of 20 years of severe, unrelenting depression. "You felt like a dead person walking. There was just nothing left in me." Diane, who's 54, was prescribedoneanti-depressant after another and psychotherapy.
Nothing worked. She tried to commit suicide three times. "It was unbearable. It was just unbearable." Finally, her psychiatrist suggested a radically different, experimental treatment - deep brain stimulation. The same procedure used safely for two decades to calm the tremors of Parkinson's disease is now being tested on severe depression.
"We slowly advance this probe into the brain. And it goes to the precise location where there's abnormal activity going on, resulting in depression." "And what do you do once you're there? " "We activate it by sending precise tiny electrical signals." "So, these electrical pulses change someone's mood?" "That's correct."
Watch what happens to Diane. With her head in a brace, so it cannot budge, and the electrodes deep inside her brain, doctors start adding those electrical pulses. "I'm starting to smile. I feel happy." "You feel happy?" "Uh-huh." Minutes later, doctors increase the electrical intensity, and Diane's mood improves further. "It felt good." "When was the last time you felt like this?" "Oh, I can't even remember when."
Then, another tweak and those electrical pulses get even stronger. "Just feel happier." To keep her depression-free, doctors then implant these pacemakers in her chest, and bury the wires under her skin, so that those electrical pulses keep flowing into her brain. "This is how you really are? " 'This is me, yeah." "This was you before the depression?" "Yes. Yes." "Happy to be back?" "Oh, it's so wonderful." So wonderful to feel so alive. Cheers. Cheers. John Mckenzie, ABC News, Norwalk, Ohio.
cutting-edge : 첨단의 (state-of-the-art = sophisticated) * cutting edge : 최선두, 최첨단 * at/on the cutting edge of something: ex. These models are at the cutting edge of computer psychotherapy : 심리[정신] 요법, 심리치료 relief : (고통 걱정 곤궁 등의) 제거, 경감, 안심, (빈민 ·난민 등의) 구제, 구원 ex. It was a great relief for me to hear that. 그 말을 듣고 안심했다. ex. The patients experienced no relief from their symptoms. * breathe a sigh of relief : We breathed a sigh of relief when Gustav went home. 안도의 한숨을 쉬었다. * relieve : <고통·고민·불안 등을> 누그러뜨리다 경 감 [완화] 시키다 (mitigate), <남을> (곤궁·탄압 등으로부터) 해방시키다, 구제하다 ex. relieve a person of one's responsibility 책임을 면해 주다. crystal clear : (수정처럼) 맑고 투명한, 매우 분 명한 reminder : 생각나게 하는 사람 [것], 상기 시키는 것 * remind : 생각나게 하다, 상기시키다, 일깨우다 ex. He reminds me of his brother. 그를 보니 그의 동생 생각이 난다 / ex. Please remind her to call me. 그녀에게 잊지 말고 전화해 달라고 일러 주 시오 ex. Remind him that I'll come tomorrow. 내일 간다고 그에게 일러 주게 / ex. That reminds me. 그러고 보니 생각난다 unrelenting : (= relentless) 가차[용서] 없는, 엄한, 무자비한, <힘·속도 등이> 꾸준한 ex. They have been unrelenting in their support for the local community. ex. unrelenting heat/wind/pressure prescribe : 명령하다, 지시하다 (order), 규정하다, 처방하다 ex. Do what the law prescribes. 법이 정하는 바를 하여라. ex. He always prescribes to us what (we are) to do. 그는 항상 우리들에 게 해야 할 바를 지시한다 ex. The attending physician prescribes the medicines for his patient. 주 치 의는 환자에게 약을 처방해 준다. anti-depressant : 항(抗)우울증의, 우울증을 치료하는[진정시키 는], 항우울제 * depressant : 진정[억제] 효과가 있는, 의 기소침하게 하는, 진정제, 강하제 one after another : 하나씩 하나씩, 차례차례, 잇따라. ex. They disappeared one after another. psychiatry : 정신 의학, 정신병 치료법 * psychiatrist 정신병 의사 [학자] radical : 근본적인, <사람 사상 등이> 과격한, 급진적 인, 과격론자, 급진분자 ex. a radical group 과격 단체 stimulation : 자극, 격려, 고무 calm : <바다.날씨 등이> 고요한, 잔잔한, <마음.기분 등이> 평온한, 차분한 vt., vi. 가라앉히다, 가라앉다, 무풍, 잔잔함, 고요 ex. the calm before the storm 폭풍우 전의 고요 tremor : (몸 손 목소리 등의) 떨림 advance : ~을 나아가게 하다(push forward), 전진시키다, 진보시키다, <돈을 > 선불하다, 가불하다, 전진, 진보, 선불, 가불 ex. I advanced him some money on his wages 급료를 가불해주었다. ex. She was paid a $100,000 advance for her next two novels. probe : [외과용 의] 탐침 (探針), 우주 탐사선, [불법 행위 적발을 위한] 철저한 조 사, 정밀 검사, ~ 을 탐침으로 찾다, 정밀검사하다 abnormal : 비정상적인 * abnormality : 이상, 변칙, 비정 상적인 것, 변칙적인 것, 기형 result in : (~ 의 결과로) 되다, ~ 의 결과를 낳 다, 귀착하다 * result from ~ 에서 기인 [유래] 하다 ex. His efforts will not result in failure. 그의 노력은 실패로 끝나지 않을 것이다. activate : ~ 을 작동시키다, ~ 을 활성화하다 brace : 버팀대로 받치다, 바싹 죄다, 버팀대, 꺾쇠 * brace for~ ~ 에 대비하다 , ~ 에 대비하여 마음의 준비를 단단히 하 다. * brace yourself for something: ex. He braced himself for the shock. 그 는 충격에 대비해 마음을 다잡았다. * brace yourself to do something: ex. Smith braced himself to deliver the bad news. * She braced herself against the wall. 벽에 몸을 밀착시켰다. budge : [보통 부정구문] (조금) 움직이다 [움직이게 하 다], 태도견해를 바꾸다 electrode : 전극, 전극봉 (棒) tweak : 1. to pull or twist a part of someone's body 2. to make small changes to improve something 3. a pull or a twist 4. a small change that improves something부분적인 개선[개량] ex. Henry leaned forward and tweaked my ear playfully. ex. It still needs a few design tweaks. ex. He gave the boy's nose a gentle tweak. implant : <주의 사상 등을> 주입하다, 불 어넣다, <살아 있는 조직 등을> 이식하다, 착상시키다, (수정란이) 착 상하다, 신체에 이식되는 조직편 pacemaker : 페이스메이커, 심장 박 동 조절 장치, 맥박 조정기, (뇌의) 신경 조정기, (다른 주자 기수 등에서) 선두에 선 속도 조정자, 페이스메이커